Heffter President Dave Nichols on Sirius XM’s Doctor Radio


February 6, 2017

Heffter Research Institute President Dr. Dave Nichols recently appeared on Sirius XM’s “Doctor Radio” show, where he discussed the latest psilocybin news and future research plans.

Along with Dr. Matthew Johnson, Associate Professor of Psychiatry and Behavioral Sciences at Johns Hopkins, Dr. Stephen Ross, Associate Professor of Psychiatry at NYU, and Dinah Bazer, an ovarian cancer survivor who participated in a psilocybin study in 2011, Dr. Nichols reviewed the recent findings from New York University and Johns Hopkins that show a reduction in depression, anxiety and existential distress in cancer patients. Studies showed success in treating this type of distress for months at a time with only a single dose.

Click here to Read More

Heffter's Plans for Future Research

  December 22, 2016

With Phase 2 studies on cancer-related depression and anxiety now complete, Heffter is excited to investigate other conditions that might be successfully treated with psilocybin.

Drawing on the scientific expertise and longstanding partnership of the world’s leading investigators of psychedelics, Heffter mentors the next generation of psilocybin researchers and therapists, vets new approaches, supports proof-of-concept studies, and gathers the evidence base for therapeutic treatments that, pending FDA approval, will be available to patients in need.

Click here to Read More

Heffter Research Winter 2016 Newsletter



  December 16, 2016




2016 has been a watershed year for the Heffter Research Institute and its programs! We believe that our work is contributing to what we hope will be a paradigm shift in the way that many psychiatric and addictive disorders are treated. We hope you enjoy reading about all of the great things we have accomplished this past year.

Johns Hopkins and NYU Studies of Psilocybin for Anxiety and Depression in Cancer Patients

Our big news is the publication of two Heffter-supported studies on psilocybin treatment of anxiety and depression in cancer patients at Johns Hopkins and NYU on December 1. You can access the free full-text articles by clicking on those links.

Click here to Read More

Heffter-Funded Studies Find Psilocybin Therapy Dramatically Reduces Anxiety and Depression in Cancer Patients

December 1, 2016


Two randomized controlled trials published today in The Journal of Psychopharmacology report unprecedented findings on the use of psilocybin to dramatically reduce anxiety, depression and existential distress in cancer patients.

These two studies — reviewed and funded by the Heffter Research Institute and conducted by the NYU School of Medicine and Johns Hopkins University — showed that a single dose of psilocybin, in conjunction with psychotherapy, produced rapid, robust and enduring (for more than six months) antianxiety and antidepressant effects in patients with life-threatening cancer diagnoses.

“These findings, the most profound to date in the medical use of psilocybin, indicate it could be more effective at treating serious psychiatric diseases than traditional pharmaceutical approaches, and without having to take a medication every day,” said Heffter Medical Director George Greer.

Click here to Read More

Survey of Difficult Psychedelic Experiences

October 5, 2016


The recent survey of difficult recreational psilocybin experiences by Heffter Board member and researcher Roland Griffiths, Ph.D. and his team at Johns Hopkins University draws two main conclusions that at first may seem contradictory. On one hand, psilocybin use outside the medical setting occasionally involves traumatic and potentially harmful experiences, as well as occasionally dangerous behaviors. On the other hand, most people report improvements in their quality of life after these difficult experiences.

The medical research setting provides crucial protections from harm that the recreational setting does not: a psychiatric evaluation to exclude subjects with a history of a serious mental disorder that could recur with psilocybin. Another key protection is the presence of specially trained psychotherapists with experience administering psilocybin to support subjects through distressing and confusing experiences, which can happen to anyone in any setting. Finally, the medical research setting provides hours of both pre-session preparation and post-session integration psychotherapy sessions to help the subject maximize the benefit from the session and ensure the positive impacts are enduring.

Click here to Read More

Heffter President David Nichols On 50 Years Of Research

April 16, 2016

Please join Heffter Research Institute President and co-founder David Nichols for his presentation “Nearly Half a Century Studying Psychedelics,” an overview of his pioneering career in the field of psychedelic research. Dr. Nichols will appear at 7:00 PM on Saturday, April 30th, at the California Institute of Integral Studies in San Francisco.

“Beginning with his graduate studies in 1969, Dr. David Nichols began research on drug molecules known then as ‘psychotomimetics.’ This talk will roughly chronicle his journey from 1969 until the present, presenting advances in the evolution of thinking about these drugs, now popularly called psychedelics.”

Nearly Half a Century Studying Psychedelics with David Nichols