Psilocybin in the Treatment of Obsessive-Compulsive Disorder

This study is the first clinical use of a psychedelic in the United States in more than 30 years. All the patients were beyond the reach of standard treatments, and all responded well. One patient had symptom remission for weeks following one psilocybin session. This study shows a potential breakthrough treatment for obsessive-compulsive disorder, a recalcitrant disease that is the fourth most common outpatient psychiatric problem. The study was conducted by Dr. Francisco Moreno, M.D. at the University of Arizona Medical Center, and published in 2006.